Modulation of Cellular Function Through Immune-Activated Exosomes
نویسندگان
چکیده
منابع مشابه
Exosomes: Mediators of Immune Regulation
Extracellular Vesicles, including exosomes, are small membrane fragments released from many cell types, like Mesenchymal Stem Cells (MSCs). They were recognized as a mechanism of intercellular communication. They can transfer proteins, lipids and nucleic acids to other cells. Thus, they have many physiological (angiogenesis, coagulation and tissue repair, etc.) and pathological (e.g. in autoimm...
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Exosomes play important roles in many physiological and pathological processes. However, the exosome-cell interaction mode and the intracellular trafficking pathway of exosomes in their recipient cells remain unclear. Here, we report that exosomes derived from K562 or MT4 cells are internalized more efficiently by phagocytes than by non-phagocytic cells. Most exosomes were observed attached to ...
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Cellular Basis ofImmune Modulation is the ninth volume in the series Progress in Leukocyte Biology and comprises the proceedings of the nineteenth International Leukocyte Culture Conference. This volume is divided into 13 sections of leukocyte biology, such as "T cell Activation," "Cytotoxic Effector Cells," and "Hemopoiesis and Lymphoid Development." The first three sections include an essay o...
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Cellular prion protein (PrP(C)) is a glycophosphatidylinositol (GPI)-anchored protein, of unknown function, found in a number of tissues throughout the body, including several blood components of which platelets constitute the largest reservoir in humans. It is widely believed that a misfolded, protease-resistant form of PrP(C), PrP(Sc), is responsible for the transmissible spongiform encephalo...
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The inflammatory response to injury and infection, although an essential part of immune function, carries the risk of severe tissue depletion and immunosuppression. These outcomes increase morbidity and delay recovery. Evidence is accumulating that single-nucleotide polymorphisms in the genes controlling pro-inflammatory cytokine production adversely influence the response. Immunonutrition prov...
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ژورنال
عنوان ژورنال: DNA and Cell Biology
سال: 2015
ISSN: 1044-5498,1557-7430
DOI: 10.1089/dna.2015.2884